Saturday, April 18, 2009

What does "host" mean in the preparation of an antibody?

Antibody supplies refer to "host" as say a "mouse" for example; but then they go on to say mouse anti-goat. Please explain what the mouse and anti-goat mean.


the example to which you refer means that a protein from a goat was injected into a mouse ( the host ) and the mouse produced antibody against the goat protein. So the product would be a mouse antibody against goat protein or mouse antigoat ( protein name ). The host is the animal developing the antibody response against the antigen .In the example above the goat protein acts as an antigen for stimulating the mouse immune system to produce antibody...therfore the mouse is the host animal. It gets a lirtle confusing when the antigen is an antibody and when injected in a host animal ( the species have to be different ) the host develops an antibody against the other specie's antibody.....

"host" cells for predator microbes , you and/or mouse nothing more than a conglomeration of cells microbes ( well in your and mouse body may be in unison )

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